|Sounds like one of your drivers and probably the Video Card driver. Safe-Mode loads Windows with no Drivers and that is why your icons are so big. Find out who manufactures the Video Card and download the latest driver. |
To confirm it is the Video Driver goto you Device Manager and Uninstall the driver for the Video card and reboot.
If it boots ok it will detect new hardware and want to install a Video driver. Don't let it just Cancel the Add Hardware wizard and get on the internet to download the latest driver.
If it does not boot then it is another driver or not a driver issue at all.