|You need to be careful with multiple antivirus programs, you should not have more than one monitoring your system at any one time, the others must have their monitoring disabled (or uninstall them. Ideally you need one antivirus/antispyware program that you can trust to run full time, one firewall (windows firewall is fine), and you can have a program like Malwarebytes to do periodic scans for nasties that your AV program might have missed.|
On the probability that you have conflicting AV programs, uninstall all except the one you are keeping, keep Malwarebytes (or download), update and check all settings. If you have trouble staying on long enough to uninstall, open Task Manager and shut down anything running that you do not need, and then retry to uninstall. If you have not scanned with malwarebytes, do so when you are clear of conflicts.
If you are still having lock up problems and want to try a system restore, make sure that you pick a date a long time before you had any virus infection issues. Some believe that you should clear out all restore points after a virus attack recovery to be sure that one is not hiding in there by turning off system restore, and a little bit later turning it back on again and creating a new system restore point as a base line when all is clean again.
You have to be a little bit crazy to keep you from going insane.
If all else fails, read instructions.