|We have no idea what's going on, you didn't provide enough info. But safe mode is there for a reason...to fix whatever the problems are.|
Did you recently install anything that may have brought this on? Software? Drivers? Since you've been in safe mode, have you tried running your anti-virus or anti-malware programs to see if there's an infection? Have you checked the startup list to see if some rogue program has somehow installed itself?