|The registry has it's own find (Edit > Find) but the mere fact that you are asking such a basic registry question makes it seem you are not competent to be going there. If this is the case you could easily wreck things.|
XP does not need folders to be open in order for it to find their contents, provided you are doing it via the Start button or the right place in Windows Explorer.
It would be far better to let us know what the problem is you are trying to fix.
Always pop back and let us know the outcome - thanks