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Here is how to fix Windows 10 Cumulative Update Failed KB3081424 error
1 – Press windows key + r on your computer. In the run box type regedit and click ok.
2 – In the registry editor which appears browse to the following path given below from the left menu.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList
3 – Now, in the ProfileList find keys having this combination s-1-15-21-some_long_numbered_key_here
Your explanation is incomplete plus there's another way that's easier, especially for those who don't like to poke around in the registry. Manually install KB3081440 to fix the problem with KB3081424.
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