|I use Media Player Classic which does most media outputs.Music and DVD's.|
Best free AV programs, which can all be found on CNET Downloads:
Microsoft Security Essentials
Best paid for AV programs which can all be found on CNET Downloads:
These are my own opinions and there are lots of "experts" on here that will disagree, so try reading reviews on all AV programs you are interested in, not just my suggestions and test them for yourself, most will offer free trials.
Look for things like Realtime Scanners and Behavioral Detection Scanners which are your best defenses against infections, also support options for when you have problems or viruses. It has to incorporate a good firewall as well.
Also you should download and use Malwarebytes regularly to assist your AV program.