|This notepad.exe program is a program that would have been preinstalled on your computer, as this program is a Microsoft program that is on all Windows computers. This is known as Microsoft's notepad program for writing memos or other small text files. This is not a spyware and virus, but make sure the name is not n0tepad.exe (notice that is a zero and not the letter o). N0tepad.exe (with the zero) is a spyware or virus related program that is trying to fool you into thinking that is a safe program. Spyware writers will try to take advantage of common names like this, so check your file location and name if you are suspicious of a virus infection. Visit notepad.exe for complete information on this task or process. If you would like help on other tasks or processes, you can view the entire process and task directory in below url.|
If the file name in the location is correct in the mean time the problem may continue you check it this problem will causing by Autorun.inf also..
If you are using Original windows you can try it Microsoft Essential Security by the following link.
or you may try with Avira Antivirus