|I can't speak to what will happen to Outlook, but as far as Word, Excel, Powerpoint, etc are concerned, be carefull.|
If you have an xlb file (for any customized Excel tool bars), a personal.xls for Excel macros, a normal.dot file for Word macros, or any similar files for your Office apps, you should make backup copies and store them someplace other than where they reside by default.
Depending on what you repair or reload, these files may be overwritten or simply deleted. BTDT
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