Thanks a lot. In Windows 7 with IE9, when I click on "Download" in the Gmail window, I'm given options to "Open", "Save", "Save As", "Save and Open" or "Cancel" (which is new and unfortunately what caused the issue). I selected "Open". This opened the document in Excel. I then edited the document for an hour or two and saved multiple times (unless I'm imagining this). The original document is still attached to my Gmail e-mail, but this does not have all of my edits.
I've checked "My Documents" and "Downloads", but it's not in either. I've also searched my hard drive for *.xls* and *xls*, but it's not showing up. I've searched my hard drive for *, and this also turns up nothing.
Interestingly, however, when I do the same thing (open an Excel spreadsheet from Gmail) with another e-mail and then search for * while the document is still open, it does not show up. It's almost as though the document is stuck in an Internet Explorer cache as part of the program and is not actually present on the hard drive.
When you said to look in Application Data, I became hopeful because I had not looked there before (other than with the global hard drive search), but it doesn't seem to be there either.
Curious if someone can try to recreate what I experience when I "Open" a document as described above and see if the document is present on their hard drive (with same IE9 and Windows 7 setup).
Thanks again for the suggestions.