|As the document is usually saved before its sent, i would tend to say no.|
However, depending on how you are sending the document. its possible.
For example if you were to open Word, Write your document, and use the Send To Mail Recipient option before saving.
It could possibly get corrupt or distored if your MAPI was broken.
Read here: http://community.office365.com/en-u...
If this is how your sending the word dcouments when they get "corrupt", try creating a new one.
Save it to your desktop.
OPen outlook, Open a New Mail Item, and attach it and send.
Doees it still happen?
You can also test this by sending the same document using say outlook express.
Or even try sending it from an free online POP Email Account like Hotmail.
How did you get on with the above?
Was SP2 installed?
Did you try it in safe mode?