Your board has a pci-e slot, so yes it will work. The limiting thing would be your power supply. The 460 needs a 450 watt psu with 26 amps on the 12 volt rail. Post back with your specs if you have any questions.
OK, but if you would have asked first, I would have suggested, along with a lot of other techs, that you a psu with a single 12 volt rail. Why did you buy a psu with 4 rails? I see Antec makes a 650 with a single rail.
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