|If the drive was installed as your boot drive actually booting - even with noises then I would encourage you to "immediately" copy "all" your personal files etc to external storage; typically DVD but an external hard drive too is nice(r). But you appear to suggest it's a usb drive?|
Based on my limited experience I'm inclined to view that the drive is failing - if it hasn't already failed. Clicking noise invariably means the drive is on its way out...
Regardless of the problem drive - now would be a good time to save your files (on the actual working computer) and then set about resolving the external drive noises... (which if it is failing are beyond the average user's ability...). Why save the those files (copy them to external media)? At some stage you may wish you had - should there be any problems with the working system that put your files on its drive at risk.
Re' the "usb drive: remove it (if you) can from its case; wrap in paper towel; place inside a plastic bag - the type used for sandwiches or freezing... Squeeze out the air; place bag and contents in the freezer for about an hour. Remove from freezer; open bag and loosen (do not remove) the paper towel wrapping. Leave it sit for about 20mins or so. Then re-install into its case and see if it will spin up when reconnected to the working computer. If it will - immediately set about copying its contents to DVD.Likely it will stop at some stage; if so repeat the cooling process and try again...etc.. chances are you may revive it long "enuff" to recover all data; but possibly not.
If you can't remove the drive from its case; put the whole assembly in the freezer as above... and proceed as above.
Sadly drives do die; and often clicking noises are a symptom, as are "screeching noises..."
Medion generally use decent drives (at least that's been my limited experience). Some of their kit in the past has actually been Acer rebranded (older laptop etc. models). Some of their kit may even have been Sony (audio kit etc...)