WD Hard Drive -- Poof!

I was using my external drive yesterday and it started acting sluggish - then I noticed about 75 folders worth of music are missing (I'm a DJ). Most of the older folders are still there - and I was even able to move a file from the drive to my laptop desktop. BUT I can't really get on the drive without it acting severly sluggish, whenever I click on my main folder it says "E: isn't formatted" (it was). I've tried to run PC Inspector and Pandora Recovery and neither have worked. I ran "Analyze" on Disk Defragmenter and it says it cannot because there is corruption in E:/MPB. Any ideas as to what to do?

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