Are you unable to reboot at all? If so you may have to remove your harddisk and connect it to another computer through an incloser or something and delete the hidden c:\hiberfil.sys file from it. After that get trendmicro house call: http://housecall.trendmicro.com/ and malwarebytes: http://www.malwarebytes.org/ and do a deep scan of your computer.
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