|- Internal HDD (hard disk drive), External USB HDD?|
- Model # of HDD?
- It does this on the same PC as you always use, or is this a different PC?
- Any Virus issues?
- If it's an external drive, what is dropped or mishandled at all?
Sounds like maybe the drive could be corrupt or have some surface or electronics issues. You could test it with a HDD test utility, depending on the make of the HDD. You could also maybe try to scan it with Windows CHKDSK utility.
Just another stupid saying...