|Not to over-ride OtheHill's suggestion but I have installed the MS utility but found no value in it but...|
Right click on your desktop and select Properties.
Got to Appearance tab, Effects and place a check next to "Use the following method to smooth edges of screen fonts" also selecting "Clear Type" from it's drop down menu.
The utility offered by MS is the Clear Type Tuner utility that I, personally, decided not to mess with. Perhaps you may want to?
I used to prefer the 800x600 resolution but so many websites today use the 1024x768 that the 800x600 does not work so good. Once you get used to the 1024x768 (and get new glasses:) you too may find it better.