|Well, I can't see your setup, but I would first check to see if you have the proper port selected in the HotSync menu.|
Local, USB, Modem etc.
If that is set correctly, maybe you could uninstall the program, after backing up your data and reinstall.
Believe me, I know how frustrating Pam's software can be. Love the product, not real thrilled with the software.
Chuck Norris was once asked why he doesn't use an iPhone, he responded, "Same reason I don't use tampons."