My cd-rom drive does not work after Windows XP is loaded. I have uninstalled and reinstalled the drive. I have adjusted the registry (deleting upperfilters and lowerfilters) according to Microsoft's instructions and it still does not work. The drive is listed in my BIOS, but it will not work after Windows XP loads. Any suggestions on what I might try beyond what I have already done?

"but it will not work after Windows XP loads" Does that mean it works before XP loads. Like for instance, you can boot a bootable cd from it

Yes, it does work before XP loads. I can boot a bootable cd from it. After XP loads, the drive is listed in Device Manager. However, when I try to push the button to open the CD-ROM drawer, it does not open and then Device Manager no longer list the drive. My DVD device and CD-ROM device are connected to the motherboard by the same ribbon wire and the DVD device works perfectly after XP is loaded.

Check the Jumpers on the Drives The CD-ROM should be Master and on the end plug of the Ribbon Cable, with the DVD as Slave. Some systems my use Cable Select. Check your system Specs. To use Cable Select Place the CD-ROM on the end plug and both drives jumpered for Cable Select. There is nothing to learn from someone who already agrees with you.

My computer is set with the DVD as the master and the CD-ROM as the slave. It came that way when I bought the computer 7 years ago. This system has work perfectly for all that time until recently. I have not changed the jumpers at any time. Any others suggestions?