Okay ive seen this post before but didnt pay attention because I didnt think I would run across it. Sister just told me that she cannot run defrag on her computer because a file in one of her music folders and she cannot delete the file because it says it is in use by a application. She does have a file sharing program. She says all applications appear to be closed but still cannot delete the file. Anyone with limewire or kazaa had this problem and has the answer?

Try to log on as a different User with Admin Rights and see if you can delete the file.

I hate to tell you this but It sounds like you have what I had a week ago, fortunatly for me I had this problem before and it is a virus or trojan loaded.. better put downloaded on your pc. I find pressing Ctrl Alt Del and looking for unusual processes running on your pc and ending them will end the in use notice. carefull what you download ALWAYS! even this mornings updates are out of date.