Avast Antivirus , works great and its free. Been using it for a year now .Autmatic updates if configured. AVG is not an option any more for winme users . Version 7 is coming to and end and version 8 no longer supports ME. It was a good AV while it did support ME . Don't think Avira is an option either , looked at the system requirements and ME is not on the list. Avast is the last free AV that I know of that supports ME other than online scanners.
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