Are these the only two programs not responding, or is it the same with all programs?
If a shortcut is used to open the program, verify that it points to the correct file.
Try turning off the antivirus program.
Disable as many of the programs that load at startup as possible and then restart the computer. Then, try running the application again. If that doesn't help, try running the application in Safe Mode. If the program does not work in Safe Mode, try uninstalling and reinstalling it.If it works in Safe Mode, the program itself is probably OK, and the problem may caused by a conflict with something loading at startup.
To this effect, suggest one of the following:
-Click Start>Run, enter: msinfo32 (or msinfo (whatever works)) The Microsoft System Information window appears.
-In the left side pane, click on the (+) of Software Environment to expand it, and then select Startup Programs. A list of all these appears on the right side pane.
-On the menu bar, click: Edit>Select All to highlight the entries on the right pane, and then click: Edit>Copy.
or, better yet,
Download StartUpList from www.spywareinfo.com. Extract it, double click on it, and it will generate a text file (NotePad) listing items loaded when Windows starts. To copy, go to Edit on the menu bar, and click on: Select All. After all the entries are highlighted, go back to Edit>Copy.
Whichever option is chosen, paste the copied text on this post to check out if there is something lurking in the background causing the problem.