No, rloew's RAM patch can be applied at any time to an installation AFTER VMM32 is compressed during the second round of SETUP. You can manually patch the files beforehand, but this is not necessary.
"Probably because we used 95/98/ME back in the days when it was practical to do so, but there's little need to do so in 2016. And if I did have a need, I'd cobble together a system with Win98 era specs. Of course, I have a plethora of vintage components so it would be easy for me; probably not so easy for others."
Oh well, to each his own. IMO, foolish to falsely limit the capabilities of an operating system to far less capable hardware though. But the point was that yourself and others here always treat the RAM issue like it can be solved with "tweaks" (which does NOT work in all cases) and if someone does happen to mention the patch, it is always treated as some arcane unknown quantity. There's a free demo. Try it. Then you will know it works.