Microsoft HCL (hardware Compayability list doesn't even show this Scanner). Plenty of other Epson though, GT-5000, 5500, 8500, 9500.
http://www.microsoft.com/hcl/results.asp
Also Epsons Web Site does does NOT have Drivers for Windows 2000.
http://www.epson.com.my/download/pages/Windows_2000_Product_Category/Scanners/
If you really reallly want to try that scanner, maybe use the 8500 or 9500 driver. Or try windows XP which has built in imaging support.
If the manufacturer does not provide drivers and there are NO embed drivers, your SOL. Unless one of the Others works (as by chance). Good Luck