No the max MTU remains the same, but the payload for e-mail is small if you're just STAT'ing
I assume this is pop3/smtp, if you:
sent or recieved an e-mail in OE, then MTU is probably not the issue
but, if 'send/receive' was just clicked, with no new messages received, and no errors, it could possibly be a mismatched MTU. (your MTU is higher or lower than the receiving end's)
But, thats just a guess...in reality, the IE 'cannot find servr/dns error' is rather generic and doesn't point to one specific problem...dns can be working and IE will still report that error.
You'd need to do some more testing, verify if you can send an e-mail, try a differnet browser, see if you can get a ping reply from a host name.
If the e-mail server is a hostname, and not a numbered IP address, then DNS is functioning properly...
But, If e-mail servers are IP addy's, and PING'ing google.com fails w/ 'unknown', then it is a DNS issue.
I don't really have enough info to diagnose...
But, you need to try and narrow the issue down, because the IE 'cannot be displayed' error is not a reliable troubleshooting message.
and good luck if it is an ISDN issue. ISDN is rather complicated, and I've barely scratched the surface. Don't you have some kind of a sysadmin to work w/ the ISDN connection?