|Sounds like temporary file pft10C.tmp was removed but its registry entry remained.|
I don't rate cleanup programs or registry cleaning because they often mess things up. However when needs must:
Download and install CCleaner and run its normal cleaner.
Next go to the registry section, run it to see what it finds. Untick everything except any reference to pft10C.tmp and let it remove it. Of-course you might be safe to let it remove all invalid registry entries but that it could backfire.
An alternative is to type msconfig in the Run box and see if pft10C.tmp appears in one of the paths in the Startup tab. If so, untick it (which cures the "symptom" but leaves an unused registry entry in place).
It doesn't seem like any sort of SpyBot or virus to me.
Always pop back and let us know the outcome - thanks