Formatting seems pretty drastic. What you've got is a tenacious pest but its fixable. Go to your task manager and check to see if 'pup' is running. If it is close it. Then delete all of the files in your temporary internet files folder. Your going to have to search your c: drive and registry keys for the following: pup, winpup, sysu, internet optimizer, ddm, dd_m, and amcompat and delete them. Also check for a string of random numbers. I have encountered 2831667, 3644961, 1923769, 70399111, 819118657, or 35575503 and delete them. I suspect 'pup' randomly creates numbers so when you check your registry actually look to see if you see any string of numbers like the above in the folders containg 'pup', 'winpup', etc and then check your c: drive and registry for that\those number(s). I would strongly recommend taking a snapshot of your system using the system restore function under system tools before deleting ANYTHING. Also run MSCONFIG and see what you have running during startup.
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