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Looks like I'm not the only one with trojan/malware troubles! After perusing the other posts I downloaded MalwareBtye from Majorgeeks, when I try to install it McAfee blocks the app and gives this message:
"McAfee has automatically blocked and removed a Trojan.
About this Trojan
Detected: Generic.dx (Trojan), Generic.dx (Trojan)
Location: C:\Program Files\Malwarebytes' Anti-Malware\is-ISAOC.tmpTrojans appear as legitimate programs but can damage valuable files, disrupt performance, and allow unauthorized access to your computer."
Should I disable McAfee before running Malwarebyte, or did I download a bogus version?

Try it this way, go offline, disable McAfee and run Malwarebytes. Restart the computer to get McAfee running again and post the Malwarebytes log.
Please download and install the latest version of HijackThis v2.0.2:
Download the "HijackThis" Installer from this link:
Hijack This
1. Save " HJTInstall.exe" to your desktop.
2. Double click on HJTInstall.exe to run the program.
3. By default it will install to C:\Program Files\Trend Micro\HijackThis.
4. Accept the license agreement by clicking the "I Accept" button.
5.Click on the "Do a system scan and save a log file" button. It will scan and then ask you to save the log.
6. Click "Save log" to save the log file and then the log will open in Notepad.
7. Click on "Edit > Select All" then click on "Edit > Copy" to copy the entire contents of the log.
8. Paste the log in your next reply.
9. Do NOT have HijackThis fix anything yet! Most of what it finds will be harmless or even required.

OK - I've got MalwareByte running and downloaded Hijack This, will post their logs when they're finished.
I've had a couple people tell me to ditch IE and McAfee and go with Firefox and Avast; are those really the best options? If so, got a reliable site I can download or purchase them from?

OK, here's the MalwareByte log:
Malwarebytes' Anti-Malware 1.28
Database version: 1235
Windows 5.1.2600 Service Pack 310/6/2008 6:02:27 PM
mbam-log-2008-10-06 (18-02-27).txtScan type: Full Scan (C:\|D:\|E:\|)
Objects scanned: 103871
Time elapsed: 23 minute(s), 41 second(s)Memory Processes Infected: 4
Memory Modules Infected: 2
Registry Keys Infected: 15
Registry Values Infected: 2
Registry Data Items Infected: 7
Folders Infected: 1
Files Infected: 9Memory Processes Infected:
C:\Program Files\Applications\iebtm.exe (Trojan.Zlob) -> Unloaded process successfully.
C:\Program Files\Applications\iebtmm.exe (Trojan.Zlob) -> Unloaded process successfully.
C:\Program Files\Applications\wcm.exe (Trojan.Zlob) -> Unloaded process successfully.
C:\Program Files\Applications\wcs.exe (Trojan.Zlob) -> Unloaded process successfully.Memory Modules Infected:
C:\WINDOWS\system32\590075\590075.dll (Trojan.BHO) -> Delete on reboot.
C:\Program Files\Applications\iebt.dll (Trojan.Zlob) -> Delete on reboot.Registry Keys Infected:
HKEY_CLASSES_ROOT\TypeLib\{e63648f7-3933-440e-b4f6-a8584dd7b7eb} (Trojan.BHO) -> Delete on reboot.
HKEY_CLASSES_ROOT\Interface\{f7d09218-46d7-4d3d-9b7f-315204cd0836} (Trojan.BHO) -> Delete on reboot.
HKEY_CLASSES_ROOT\CLSID\{afc8a14f-b50a-4f0f-8fb7-77982092d81d} (Trojan.BHO) -> Delete on reboot.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Browser Helper Objects\{afc8a14f-b50a-4f0f-8fb7-77982092d81d} (Trojan.BHO) -> Delete on reboot.
HKEY_CLASSES_ROOT\w123.w123mgr (Trojan.BHO) -> Delete on reboot.
HKEY_CLASSES_ROOT\w123.w123mgr.1 (Trojan.BHO) -> Delete on reboot.
HKEY_CLASSES_ROOT\CLSID\{cfee97a3-4911-444d-8be8-e243a23d3de2} (Trojan.Zlob) -> Delete on reboot.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Browser Helper Objects\{cfee97a3-4911-444d-8be8-e243a23d3de2} (Trojan.Zlob) -> Delete on reboot.
HKEY_CURRENT_USER\SOFTWARE\Microsoft\Internet Explorer\SearchScopes\{daed9266-8c28-4c1c-8b58-5c66eff1d302} (Search.Hijack) -> Delete on reboot.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Extensions\{9034a523-d068-4be8-a284-9df278be776e} (Trojan.Zlob) -> Delete on reboot.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\Windows Safety Alert (Trojan.Zlob) -> Quarantined and deleted successfully.
HKEY_CLASSES_ROOT\CLSID\e405.e405mgr (Trojan.Zlob) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\IEBrowse Tool (Trojan.Zlob) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\Warning Center (Trojan.Zlob) -> Quarantined and deleted successfully.
HKEY_CLASSES_ROOT\multimediaControls.chl (Trojan.Zlob) -> Quarantined and deleted successfully.Registry Values Infected:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Policies\Explorer\Run\start (Trojan.Zlob) -> Delete on reboot.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Policies\Explorer\Run\smile (Trojan.Zlob) -> Delete on reboot.Registry Data Items Infected:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\SearchURL (Hijack.Search) -> Bad: (http://windiwsfsearch.com) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Main\Default_Search_URL (Hijack.Search) -> Bad: (http://windiwsfsearch.com) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Main\Search Page (Hijack.Search) -> Bad: (http://windiwsfsearch.com) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Main\Search Bar (Hijack.Search) -> Bad: (http://windiwsfsearch.com/ie6.html) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Main\SearchMigratedDefaultURL (Hijack.Search) -> Bad: (http://windiwsfsearch.com/search?q={searchTerms}) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\Search\SearchAssistant (Hijack.Search) -> Bad: (http://windiwsfsearch.com) Good: (http://www.google.com/) -> Quarantined and deleted successfully.
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\SearchUrl\w\ (Hijack.Search) -> Bad: (http://windiwsfsearch.com/search?q=%s) Good: (http://www.google.com/) -> Quarantined and deleted successfully.Folders Infected:
C:\WINDOWS\system32\590075 (Trojan.BHO) -> Delete on reboot.Files Infected:
C:\WINDOWS\system32\590075\590075.dll (Trojan.BHO) -> Delete on reboot.
C:\Program Files\Applications\iebt.dll (Trojan.Zlob) -> Delete on reboot.
C:\System Volume Information\_restore{D6518356-4E98-4027-AE5B-94F9CF6325E9}\RP192\A0017165.exe (Trojan.BHO) -> Quarantined and deleted successfully.
C:\Program Files\Applications\iebtm.exe (Trojan.Zlob) -> Delete on reboot.
C:\Program Files\Applications\iebtmm.exe (Trojan.Zlob) -> Delete on reboot.
C:\Program Files\Applications\iebtu.exe (Trojan.Zlob) -> Quarantined and deleted successfully.
C:\Program Files\Applications\wcm.exe (Trojan.Zlob) -> Delete on reboot.
C:\Program Files\Applications\wcs.exe (Trojan.Zlob) -> Delete on reboot.
C:\Program Files\Applications\wcu.exe (Trojan.Zlob) -> Quarantined and deleted successfully.
Here's the HijackThis log:Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 6:05:42 PM, on 10/6/2008
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16705)
Boot mode: NormalRunning processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.exe
C:\WINDOWS\ehome\ehtray.exe
C:\WINDOWS\system32\hkcmd.exe
C:\WINDOWS\system32\igfxpers.exe
C:\Program Files\McAfee.com\Agent\mcagent.exe
C:\Program Files\SiteAdvisor\6261\SiteAdv.exe
C:\WINDOWS\system32\spool\drivers\w32x86\3\hpztsb09.exe
C:\Program Files\HP\hpcoretech\hpcmpmgr.exe
C:\Program Files\Hewlett-Packard\HP Software Update\HPWuSchd2.exe
C:\WINDOWS\system32\hphmon05.exe
C:\Program Files\Java\jre1.6.0_07\bin\jusched.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Hewlett-Packard\Digital Imaging\bin\hpqtra08.exe
C:\Program Files\Nikon\PictureProject\NkbMonitor.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\WINDOWS\eHome\ehRecvr.exe
C:\WINDOWS\eHome\ehSched.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
c:\PROGRA~1\COMMON~1\mcafee\mna\mcnasvc.exe
c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
C:\Program Files\McAfee\MPF\MPFSrv.exe
C:\Program Files\SiteAdvisor\6261\SAService.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\dllhost.exe
C:\WINDOWS\system32\HPZipm12.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\WINDOWS\eHome\ehmsas.exe
C:\Program Files\Malwarebytes' Anti-Malware\mbam.exe
C:\WINDOWS\system32\NOTEPAD.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Documents and Settings\Tariq\Desktop\HiJackThis.exeR1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?Lin...
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?Lin...
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?Lin...
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {089FD14D-132B-48FC-8861-0048AE113215} - C:\Program Files\SiteAdvisor\6261\SiteAdv.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files\McAfee\VirusScan\scriptsn.dll
O3 - Toolbar: McAfee SiteAdvisor - {0BF43445-2F28-4351-9252-17FE6E806AA0} - C:\Program Files\SiteAdvisor\6261\SiteAdv.dll
O4 - HKLM\..\Run: [ehTray] C:\WINDOWS\ehome\ehtray.exe
O4 - HKLM\..\Run: [igfxtray] C:\WINDOWS\system32\igfxtray.exe
O4 - HKLM\..\Run: [igfxhkcmd] C:\WINDOWS\system32\hkcmd.exe
O4 - HKLM\..\Run: [igfxpers] C:\WINDOWS\system32\igfxpers.exe
O4 - HKLM\..\Run: [mcagent_exe] C:\Program Files\McAfee.com\Agent\mcagent.exe /runkey
O4 - HKLM\..\Run: [SiteAdvisor] "C:\Program Files\SiteAdvisor\6261\SiteAdv.exe"
O4 - HKLM\..\Run: [HPDJ Taskbar Utility] C:\WINDOWS\system32\spool\drivers\w32x86\3\hpztsb09.exe
O4 - HKLM\..\Run: [HPHUPD05] C:\Program Files\Hewlett-Packard\{5372B9A6-6E51-4f90-9B40-E0A3B8475C4E}\hphupd05.exe
O4 - HKLM\..\Run: [HP Component Manager] "C:\Program Files\HP\hpcoretech\hpcmpmgr.exe"
O4 - HKLM\..\Run: [HP Software Update] "C:\Program Files\Hewlett-Packard\HP Software Update\HPWuSchd2.exe"
O4 - HKLM\..\Run: [HPHmon05] C:\WINDOWS\system32\hphmon05.exe
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 8.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_07\bin\jusched.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - Global Startup: HP Digital Imaging Monitor.lnk = C:\Program Files\Hewlett-Packard\Digital Imaging\bin\hpqtra08.exe
O4 - Global Startup: NkbMonitor.exe.lnk = C:\Program Files\Nikon\PictureProject\NkbMonitor.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O22 - SharedTaskScheduler: impetuousities - {0ba3e00d-b660-46e6-a2db-2672ee82dc98} - (no file)
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files\McAfee\MPF\MPFSrv.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\system32\HPZipm12.exe
O23 - Service: SiteAdvisor Service - Unknown owner - C:\Program Files\SiteAdvisor\6261\SAService.exe--
End of file - 7112 bytes

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