|Look for the card in Windows Disk Management. The card will not show in Computer unless Windows can read it. If the card is formatted with propitiatory format or not partitioned and formatted at all, then it will not appear in Computer.|
Also, as stated by DAVEINCAPS, your reader may not be able to handle a high density card.
Did the card reader ever work for you with any card?
Is the reader an internal reader or an external USB reader?
Post more hardware information.