|Adapters work fine.|
To basic ways. One is to use native adapter such as ide or sata and the other is to use a usb to hard drive.
A notebook hard drive is smaller and built to take a bit more bumps. Otherwise similar in use. They tend to be very slow however.
"Best Practices", Event viewer, host file, perfmon, antivirus, anti-spyware, Live CD's, backups, are in my top 10