|First of all please do not type in all caps. That is considered shouting. |
You are asking about the settings for your OPTICAL drive. Normally, disk drives refer to the fixed hard drives in the computer.
Your settings are dependent on what programs you use to view/play the particular type of disk. For instance, if you want to use a third party music program instead of Windows Media Player then you need to select the program you wish to use.
Only you know what you want to use. Windows Media Player can play most all formats but you may not want that.
For instance, if you have photos on a CD or DVD you may want to open them in a third party program to edit, manipulate, etc.
If you have files that you are not sure of then the safe selection is to mark " ask every time"
Many times a third party program will want to hijack all file types. You may not want that either. You must read the screens when installing stuff. Camera software is an example.
Does this clarify the process for you or not?