|The easiest method, assuming your version of ghost supports it, is to simply send the image to CDR or DVDR from the start.|
If you are looking for a way to access a previously created image in order to restore it then if you have a version that is less than probably 5 years old you should be able to simply boot to the install CD and you will be given the option to restore an image that is stored elsewhere.
IMO, imaging directly to DVDR is the preferred method.
In order to keep the image size managable using multiple partitions for different types of files that would require imaging at different intervals, if at all.
This method includes installing the OS a possibly a few core programs on the primary partition by itself.
Most of your installed programs will not change very often so they don't require frequent imaging.
Your photos and music do not require imaging at all. Simple backup of that type of file is sufficient.
Look at the link below for more info on partitioning.