|Use rear ports for keyboard and mouse only.|
You can check the cable that goes from the front panel to the USB header on your motherboard and make sure it is firmly plugged in. If you have a second USB header you can try that one instead. If the wire or front jacks are bad then you can purchase a front USB add on panel with 2 or 4 new ports. The problem could be with the board itself though.
You have to be a little bit crazy to keep you from going insane.