I am not sure this will work, but you may try and it may solve your trouble.
Warning it works only for Windows XP/2K, when you are not clear about your environment, Win 9x/ME or Win 2k/XP.
1) On the desktop right click and select New Shortcut to create a new Icon/Link (sorry if I am not absolutely clear, but I'am using an italiam version of Windows XP). In the Path/target type Command.com. This will lead you to obtain a DOS-Pif link.
2) Now, right click the just created shortcut and having selected in Properties the Program sheet modify the program name as ".....\command.com /C the_name_and_path of your application"; e.g. in my system it will look like
C:\Windows\system32\command.com /C C:\ProDir\MyProg.exe
3) In the Memory sheet select "auto" or a big value in the box XMS Memory (e.g. 4096 or more).
Confirm your choice and then run the application from the shortcut on the desktop.
You may set other parameters in the Icon/Pif, but what I stated should be the essential to bypass your trouble.
I hope this helps.
Good luck