AUTOEXEC: should include something similar to:
SET BLASTER=A220 I5 D1 H5 P330
CONFIG should include something similar to:
DEVICE=C:\DOS\EMM386.EXE NOEMS NOVCPI
Last but not least run MSD and check that the Sound Card is on IRQ10 and the Graphics Card is on a different IRQ, usually 11, if another IRQ is sharing the Sound Card it causes conflicts, as per the advice about non P'n'P O/S above..............