"How Can I lock The PCI bus so I can just overclock the CPU and FBS?"
Simply put, you can't!
And once the PCI bus goes beyond the safe max of 37.5MHz, all bets are off. It's not just the sound that you have to worry about either. The video (PCI & AGP), HDDs, & optical drives all run on the PCI bus...if you increase the bus too high, you can run into all sorts of problems (data corruption, creating "coasters" when burning CDs/DVDs, distorted display).
If you have an Intel CPU, here's the safe FSB limits:
400FSB CPU @ 100MHz = 112.5MHz max
533FSB CPU @ 133MHz = 150MHz max
800FSB CPU @ 200MHz = 225MHz max